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Glycemic control is crucial for patients with diabetes mellitus as it significantly lowers the risk of renal failure. Uncontrolled diabetes leads to hyperglycemia, which can cause damage to the blood vessels, including those supplying the kidneys. This damage impedes renal function and can lead to diabetic nephropathy, a common complication of diabetes that ultimately can result in end-stage renal disease. By maintaining optimal blood glucose levels, the progression of kidney damage can be delayed or prevented, preserving renal function and reducing the incidence of renal failure.

While good glycemic control can have positive effects on peripheral neuropathy, infections, and cardiovascular outcomes as well, the direct link to renal health and the prevention of renal failure makes it particularly significant in this context. It highlights the integral relationship between diabetes management and renal preservation, underscoring the essential role of glycemic control in the overall health of patients with diabetes.