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How does chronic kidney disease contribute to anemia?

It leads to excessive production of erythropoietin

It causes blood loss solely during surgical procedures

It results from decreased erythropoietin production and blood loss during dialysis

Chronic kidney disease (CKD) is closely linked to anemia primarily due to decreased production of erythropoietin, a hormone produced by the kidneys that stimulates red blood cell production in the bone marrow. As kidney function declines, the production of erythropoietin decreases significantly, leading to a reduced ability to produce red blood cells. This contributes directly to the development of anemia in patients with CKD.

Additionally, patients undergoing dialysis often experience blood loss during the procedure itself, as well as potential nutritional deficiencies (such as iron) that can further exacerbate anemia. Thus, the combination of reduced erythropoietin production and blood loss during dialysis creates a situation where anemia is a common complication of chronic kidney disease.

Understanding this relationship emphasizes the importance of monitoring and managing anemia in patients with CKD, particularly those on dialysis, to improve their overall health outcomes.

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It has no relation to kidney function

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