Certified Dialysis Nurse Practice Test 2025 – All-in-One Resource for Exam Success!

Kidney disease significantly affects the body's fluid balance primarily by complicating fluid retention due to hormonal changes. In healthy individuals, kidneys regulate fluid balance by filtering excess fluid and waste from the blood, maintaining homeostasis through various hormonal mechanisms, including the renin-angiotensin-aldosterone system (RAAS).

When kidney function is impaired, this balance is disrupted. The kidneys may not effectively remove excess fluid, leading to fluid retention. At the same time, hormonal changes can occur, such as increased levels of renin and aldosterone, which promote sodium and water retention to compensate for perceived volume depletion. This retention can lead to symptoms like edema and hypertension, as the body struggles to manage fluid levels properly. Additionally, with chronic kidney disease, other factors, such as the accumulation of uremic toxins, can further complicate fluid management.

In contrast, the notion that kidney disease has no impact on fluid balance is incorrect because the primary role of the kidneys is fluid regulation. Increased fluid intake does not naturally occur just because of kidney disease; rather, fluid intake must often be carefully monitored. Lastly, while kidney disease can affect blood flow to the kidneys themselves, it does not restrict blood flow to all organs; this systemic impact is more nuanced and